Search on: CYCLOHYDROLASE II, GTP 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   GTP Cyclohydrolase 
Descriptor Spanish:   GTP Ciclohidrolasa 
Descriptor Portuguese:   GTP Cicloidrolase 
Synonyms English:   7,8-Dihydroneopterintriphosphate Synthetase
GTP Cyclohydrolase I
GTP Cyclohydrolase II
7,8 Dihydroneopterintriphosphate Synthetase
8-Formylhydrolase, GTP
Cyclohydrolase I, GTP
Cyclohydrolase II, GTP
Cyclohydrolase, GTP
Dihydrolase, GTP
GTP 8 Formylhydrolase
GTP Ring Opening Enzyme
Ring-Opening Enzyme, GTP
Synthetase, 7,8-Dihydroneopterintriphosphate
GTP 8-Formylhydrolase
GTP Dihydrolase
GTP Ring-Opening Enzyme  
Tree Number:   D08.811.277.151.300
Definition English:   (GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II). 
History Note English:   91(75); was see under AMINOHYDROLASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   6285 
Unique Identifier:   D006136 

Occurrence in VHL: 		 

Similar:
  
DeCS CID-10 SciELO LILACS LIS